Steve Buscemi is known for his offbeat characters — and his off-kilter smile definitely helps him play the part. But that doesn’t mean his smile is healthy. “It looks like he has gum disease, and we’d need to correct his bite,” Dr. Ritota said of Buscemi’s oral health. Gum disease can be treated with regular profession deep cleanings, medications (such as antibiotics like chlorhexidine, doxycycline, and tetracycline, or the antibiotic-containing toothpaste triclosan) or — in severe situations — surgery. Ritota also recommends braces and crowns to straighten out his smile.